Abstract

Silver nanoparticles were loaded on a covalently coupled hybrid of graphitic carbon nitride (gC₃N₄) and reduced graphene oxide (rGO) to modify a carbon paste electrode (CPE). The morphological and structural properties of this modifier (Ag–gC₃N₄–rGO) were well characterized by transmission electron microscopy, X-ray diffraction, energy dispersive X-ray spectrometry, and electrochemical impedance analysis. The performance of this constructed electrochemical sensor (Ag–gC₃N₄–rGO/CPE) was investigated by cyclic voltammetry and square wave voltammetry. The ternary Ag–gC₃N₄–rGO nanocomposite exhibited electrocatalytic properties toward isoniazid electrooxidation and effectively improved the electrochemical performance of CPE. Under optimized experimental conditions the Ag–gC₃N₄–rGO/CPE exhibited a linear dynamic range from 0.8 to 70 μM with a detection limit of 0.2 μM. The sensor was very effective for the detection of isoniazid in the presence of other reducible biological compounds and showed excellent repeatability and stability.

Graphic abstract

中文翻译：

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负载在石墨氮化碳和还原性氧化石墨烯的混合物上的银纳米颗粒，作为碳糊电极的改性剂，用于测定异烟肼

摘要

将银纳米颗粒负载在石墨氮化碳（gC ₃ N ₄）和还原氧化石墨烯（rGO）的共价偶联杂化物上，以修饰碳糊电极（CPE）。通过透射电子显微镜，X射线衍射，能量色散X射线光谱和电化学阻抗分析，可以很好地表征这种改性剂（Ag–gC ₃ N ₄ –rGO）的形态和结构特性。通过循环伏安法和方波伏安法研究了这种构造的电化学传感器（Ag–gC ₃ N ₄ –rGO / CPE）的性能。三元Ag–gC ₃ N ₄-rGO纳米复合材料表现出对异烟肼电氧化的电催化性能，有效提高了CPE的电化学性能。在优化的实验条件下，Ag–gC ₃ N ₄ –rGO / CPE的线性动态范围为0.8至70μM，检出限为0.2μM。在存在其他可还原的生物化合物的情况下，该传感器对于异烟肼的检测非常有效，并显示出极好的可重复性和稳定性。

图形摘要