Extracts of Peruvian purple corn pericarp (Zea mays L.) were obtained: (1) via supercritical fluid extraction with CO2 as solvent and EtOH-H2O (70:30, v/v) as co-solvent, (2) via pressurized liquid extraction (PLE) with EtOH-H2O (70:30, v/v) and, (3) via two conventional extraction processes, stirred vessel and Soxhlet. The extraction yields and extract compositions were compared to each other. The parameters measured were the point-to-point extraction yield, the global extraction yield and composition of extracts regarding contents of total phenolics, total flavonoids, total anthocyanins and specific anthocyanins such as cyanidin-3-glucoside, peonidin-3-glucoside and pelargonidin-3-glucoside. Antioxidant activity by DPPH and in vitro antiproliferative activity were also evaluated considering seven cancer cell lines. High yields and higher contents of phenolic compounds, accompanied by a high antioxidant activity at 50 °C, were obtained for supercritical extraction at 60 °C. Antioxidant activity showed good correlation with the content of phenolic compounds, but there was no antiproliferative activity.

中文翻译：

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紫玉米 (Zea mays L.) 果皮水醇提取物通过常规常压工艺和高压工艺获得

秘鲁紫玉米果皮 (Zea mays L.) 的提取物通过以下方式获得：(1) 通过超临界流体萃取，以 CO2 为溶剂，EtOH-H2O (70:30, v/v) 为共溶剂，(2) 通过加压液体萃取用 EtOH-H2O (70:30, v/v) 和 (3) 通过两种常规提取工艺、搅拌容器和索氏提取法提取 (PLE)。将提取率和提取物组成相互比较。测量的参数是点对点提取率、全局提取率和提取物组成，关于总酚类、总黄酮类、总花青素和特定花青素的含量，如 cyanidin-3-glucoside、peonidin-3-glucoside 和 pelargonidin -3-葡萄糖苷。考虑到七种癌细胞系，还评估了 DPPH 的抗氧化活性和体外抗增殖活性。在 60 °C 下进行超临界萃取可获得高产率和更高含量的酚类化合物，并在 50 °C 下具有高抗氧化活性。抗氧化活性与酚类化合物的含量显示出良好的相关性，但没有抗增殖活性。