Abstract Bacterial infection is a major challenge for contemporary medicine, and antimicrobial hydrogels have been extensively studied for their excellent antimicrobial activity. However, the antibacterial agent also has high cytotoxicity and hemolytic activity while being significantly antibacterial. In this paper, we prepared a hydrogel by simple heating-cooling of ZIF-90 doped agar solution, which has obvious antibacterial activity against Gram-positive and Gram-negative bacteria. The test results show that the hydrogel has a uniform and stable structure and does not exhibit cytotoxicity and hemolytic activity while maintaining good bacteriostatic properties, so as to achieve the function of bacterial infection treatment and would healthcare.

中文翻译：

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用于生物医学应用的基于琼脂的 ZIF-90 抗菌水凝胶

摘要 细菌感染是当代医学面临的主要挑战，抗菌水凝胶因其优异的抗菌活性而被广泛研究。然而，抗菌剂在具有显着抗菌作用的同时，还具有较高的细胞毒性和溶血活性。在本文中，我们通过简单加热-冷却掺杂 ZIF-90 的琼脂溶液制备了一种水凝胶，对革兰氏阳性菌和革兰氏阴性菌具有明显的抗菌活性。测试结果表明，该水凝胶结构均匀稳定，不表现出细胞毒性和溶血活性，同时保持良好的抑菌性能，从而达到治疗细菌感染和保健的作用。