Haemorrhagic transformation (HT) is one of the main risks of intravenous thrombolysis (IVT) for acute ischaemic stroke. Contraindications serve to exclude patients at high risk of HT after IVT. One of these contraindications is a stroke within the preceding 3 months. It is unclear if this contraindication should include recent clinically silent infarcts (RSIs). The aim of this study was to investigate whether RSIs are associated with a higher risk of HT and a worse clinical outcome after IVT for acute ischaemic stroke.

中文翻译：

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最近无声的梗塞不会增加静脉溶栓后出血的风险。

出血性转化（HT）是急性缺血性中风的静脉溶栓（IVT）的主要风险之一。禁忌症可将IVT后HT高危患者排除在外。这些禁忌症之一是前三个月内的中风。目前尚不清楚该禁忌症是否应包括近期的临床无症状性梗死（RSI）。这项研究的目的是调查急性缺血性卒中的IVT后RSI是否与更高的HT风险和更差的临床结局相关。