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Synthesis of Some Novel Fluorinated/Nonfluorinated α-Amino Acids, Bearing 3-Thioxo-5-oxo-1,2,4-triazin-6-yl and Steroidal Moieties, and Evaluation of Their Amylolytic Effects against Some Fungi, Part-II
Heteroatom Chemistry ( IF 0.3 ) Pub Date : 2020-07-23 , DOI: 10.1155/2020/9645949
Reda M. Abdel-Rahman 1 , Wafa A. Bawazir 1
Affiliation  

Some new fluorinated/nonfluorinated α-amino acids bearing 3-thioxo-5-oxo-1,2,4-triazin-6-yl and steroidal moieties have been obtained from condensation of the corresponding amino-triazinones with the steroid (Epiandrosterone). This was followed by the addition of HCN and, finally, acidic hydrolysis. The structure of the targets was established from their elemental analysis and spectral data. The amylolytic activity of the new products was evaluated against some fungi.

中文翻译:

一些带有 3-Thioxo-5-oxo-1,2,4-triazin-6-yl 和甾体部分的新型氟化/非氟化 α-氨基酸的合成,以及它们对某些真菌的淀粉分解作用的评价,第二部分

一些带有 3-thioxo-5-oxo-1,2,4-triazin-6-yl 和甾体部分的新型氟化/非氟化 α-氨基酸是通过相应的氨基三嗪酮与类固醇(表雄酮)缩合获得的。然后加入 HCN,最后进行酸性水解。目标的结构是根据元素分析和光谱数据确定的。评估了新产品对某些真菌的淀粉分解活性。
更新日期:2020-07-23
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