Cell-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers, and the view of each layer is reduced. Here we present curved-field optical coherence tomography, capable of capturing optical sections of arbitrary curvature. We test the device on a challenging task of imaging the human cornea in vivo and achieve a ${10} \times$ larger viewing area comparing to the clinical state-of-the-art. This enables more precise cell and nerve counts, opening a path to improved monitoring of corneal and general health conditions (e.g., diabetes). The method is non-contact, compact, and works in a single fast shot (3.5 ms), making it readily available for use in optical research and clinical practice.

中文翻译：

---

弯场光学相干层析成像：人角膜细胞和神经的大视野成像

细胞分辨率光学成像方法（例如共聚焦显微镜和全场光学相干断层扫描）可捕获样品的平坦光学部分。如果样品是弯曲的，则光场会穿过多个样品层，并且每一层的视野都会减小。在这里，我们介绍了弯曲场光学相干断层扫描，能够捕获任意曲率的光学部分。我们在对人体角膜进行体内成像的一项艰巨任务中测试了该设备，并实现了$ {10} \ times $与临床最新技术相比，视野更大。这可以实现更精确的细胞和神经计数，从而为改善对角膜和一般健康状况（例如糖尿病）的监测开辟了道路。该方法是非接触式的，紧凑的，并且可以在单个快速镜头（3.5毫秒）内工作，使其易于在光学研究和临床实践中使用。