ABSTRACT

Objectives

User experience was compared between a new pre-fillable 2.25 mL glass syringe equipped with an ultra-thin-wall (UTW) 8 mm staked needle and a marketed BD Neopak™ syringe equipped with a special-thin-wall (STW) 12.7 mm staked needle.

Methods

Participants simulated subcutaneous injections with both syringes alone (formative Human Factors study) and in combination with a needlestick-prevention device (validation Human Factors study).

Results

Usability results of both studies showed higher success rates for delivering the full dose of 2 mL viscous solution (30 cP) with the 8mmUTW syringe than with the 12.7mmSTW one (63% vs. 42% in the formative study). The use of the 8mmUTW syringe demonstrated also better ease of use and acceptance results and 72% of formative study participants preferred this new syringe over the current one when delivering the viscous solution. Using a shorter needle also showed a benefit in decreasing the injection-related anxiety. Besides, in the case of a non-recommended injection technique, the calculated risk of accidental intramuscular injection is reduced by 2 to 13 times with the 8mmUTW syringe.

Conclusion

Altogether, the results obtained demonstrated an improvement of the user experience with this new syringe compared to the current one in the manual delivery of 2 mL viscous solutions.

中文翻译：

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新型预填充注射器带有8毫米超薄壁针，可增强手动注射2 mL粘性溶液的用户体验。

摘要

目标

在使用新的预填充的2.25 mL玻璃注射器（配有超薄壁（UTW）8毫米放样针）和市售的BD Neopak™注射器（配有特殊的薄壁（STW）12.7毫米放样）之间进行了用户体验比较。针。

方法

参与者分别使用两个注射器（形成性人为因素研究）和结合防针刺装置（验证人性因素研究）模拟了皮下注射。

结果

两项研究的可用性结果均显示，与使用12.7mmSTW注射器相比，使用8mmUTW注射器输注2 mL粘性溶液（30 cP）的完整剂量具有更高的成功率（63％对42％的形成性研究）。8mmUTW注射器的使用还显示出更好的易用性和可接受性，并且在交付粘性溶液时，有72％的形成性研究参与者相对于现有注射器更喜欢这种新注射器。使用较短的针头还显示出减少注射相关焦虑的益处。此外，在非推荐注射技术的情况下，使用8mmUTW注射器可以将计算出的意外肌内注射风险降低2到13倍。

结论

总体而言，与目前手动输注2 mL粘性溶液中的注射器相比，使用这种新注射器所获得的结果表明用户体验得到了改善。