Little evidence is available regarding the prognosis of dogs with malignant ovarian tumours. The objective of this retrospective study was to describe the outcomes and determine the prognostic factors for dogs with malignant ovarian tumours following treatment, including surgery with or without adjuvant therapy. Eighteen dogs were studied, their median age was 12 years (range: 7-15 years), and their median body weight was 6.9 kg (range: 2.3-17.8 kg). Following histopathologic diagnoses revealed that granulosa cell tumour was the most common type (n = 9), followed by dysgerminoma (n = 5), and adenocarcinoma (n = 4). Eleven dogs had surgery alone. Seven dogs had surgery with adjuvant therapy, including chemotherapy and/or radiotherapy. The median survival time (ST) was 1009 days when only deaths owing to the ovarian tumours were considered, and predictors of median ST were T-category (≥ T3, 443 days vs ≤ T2, 1474 days; P = .002), presence of metastatic disease (present, 391 days vs absent, 1474 days; P < .001) and lymphovascular space invasion (present, 428 days vs absent, 1474 days; P = .003) in a univariate analysis. Median ST in dogs with granulosa cell tumour seemed longer than in dogs with dysgerminoma and adenocarcinoma, although the difference was statistically insignificant (1474 days vs 458 days, respectively; P = .10). Considering the good prognosis, aggressive treatment can be recommended for dogs with malignant ovarian tumours, especially early-stage cases. Despite metastasis being present at diagnosis, half of the dogs with metastasis survived for more than 1 year.

中文翻译：

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18只犬卵巢恶性肿瘤预后的回顾性分析

关于患有恶性卵巢肿瘤的狗的预后的证据很少。这项回顾性研究的目的是描述结果并确定患有恶性卵巢肿瘤的狗在治疗后的预后因素，包括有或没有辅助治疗的手术。研究了 18 只狗，中位年龄为 12 岁（范围：7-15 岁），中位体重为 6.9 公斤（范围：2.3-17.8 公斤）。组织病理学诊断显示，颗粒细胞瘤是最常见的类型（n = 9），其次是无性细胞瘤（n = 5）和腺癌（n = 4）。11 只狗单独进行了手术。七只狗接受了辅助治疗的手术，包括化学疗法和/或放射疗法。仅考虑卵巢肿瘤导致的死亡时，中位生存时间 (ST) 为 1009 天，P  = .002），单变量分析中存在转移性疾病（存在，391 天 vs 不存在，1474 天；P  < .001）和淋巴血管间隙侵犯（存在，428 天 vs 不存在，1474 天；P  = .003） . 患有颗粒细胞瘤的犬的中位 ST 似乎比患有无性细胞瘤和腺癌的犬更长，尽管差异无统计学意义（分别为 1474 天和 458 天；P  = .10）。考虑到良好的预后，可以建议对患有恶性卵巢肿瘤的狗进行积极的治疗，尤其是早期病例。尽管在诊断时存在转移，但有一半转移的狗存活了 1 年以上。