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IL6, IL8, and IL10 in the distinction of malignant ovarian neoplasms and endometriomas.
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2020-07-22 , DOI: 10.1111/aji.13309
Paula Carolina Arvelos Crispim 1 , Millena Prata Jammal 1 , Priscylla Kelliny Aparecida Antão 1 , Douglas Côbo Micheli 2 , Beatriz Martins Tavares-Murta 2 , Eddie Fernando Candido Murta 1 , Rosekeila Simões Nomelini 1
Affiliation  

Studies have shown a relationship between endometriosis and ovarian cancer. Our aims were to evaluate and compare the dosages of cytokines IL‐2, IL‐5, IL‐6, IL‐8, IL‐10, and TNF‐α in serum, intracystic fluid, and peritoneal fluid of patients with ovarian endometrioma, malignant and benign ovarian neoplasms, and non‐neoplastic ovarian tumors; to verify if there is a correlation between the values of these cytokines between ovarian endometrioma and ovarian malignancy; and to determine the best cut‐off point for serum cytokines that can be used to differentiate patients with ovarian malignancy and endometrioma.

中文翻译:

IL6、IL8 和 IL10 在区分恶性卵巢肿瘤和子宫内膜异位症中的作用。

研究表明子宫内膜异位症和卵巢癌之间存在关系。我们的目的是评估和比较卵巢子宫内膜异位症患者血清、囊内液和腹腔液中细胞因子 IL-2、IL-5、IL-6、IL-8、IL-10 和 TNF-α 的剂量,恶性和良性卵巢肿瘤,以及非肿瘤性卵巢肿瘤;验证卵巢子宫内膜异位症和卵巢恶性肿瘤之间这些细胞因子的值之间是否存在相关性;并确定可用于区分卵巢恶性肿瘤和子宫内膜异位症患者的血清细胞因子的最佳截止点。
更新日期:2020-07-22
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