OBJECTIVE Tumors with seizures as primary mode of presentation are collectively called Long-term epilepsy associated tumors (LEATs or Epileptomas). The overall survival is good so 'seizure outcome' becomes the primary goal rather than neuro-oncological outcome. METHODS A retrospective analysis of our surgical database (2015-19) was done to find operated patients of intra-axial brain tumors with age less than 25-years and who had presented with seizures. RESULTS The mean age at presentation was 16.44 years (SD + 6.82 years). Complex partial seizures/focal unaware seizures were the most common type of seizures encountered (n = 22) with mean duration of seizures was 49.50 months (SD + 31.04 months). The most common pathology was glioneuronal tumors (GNTs) (n = 17). Gross total resection (GTR) group had a significantly better seizure outcome as compared with the Subtotal resection (STR) group (p = 0.006). Presence of focal or partial seizure was a significant factor pointing towards a better seizure control (p = 0.005). CONCLUSION The shorter duration of symptoms, partial/focal seizures and gross total excision were predictors of a good seizure-outcome. Age of the patient and the histopathology of the tumor does not affect seizure-outcome on comparing GNTs with non GNTs.

中文翻译：

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影响儿童和青少年长期癫痫相关肿瘤 (LEAT) 癫痫发作结果的因素

目的以癫痫发作为主要表现方式的肿瘤统称为长期癫痫相关肿瘤（LEATs 或 Epileptomas）。总生存期良好，因此“癫痫发作结果”成为主要目标，而不是神经肿瘤学结果。方法 对我们的手术数据库（2015-19）进行回顾性分析，以发现年龄小于 25 岁且出现癫痫发作的轴内脑肿瘤手术患者。结果 就诊时的平均年龄为 16.44 岁（SD + 6.82 岁）。复杂部分癫痫发作/局灶性无意识癫痫发作是最常见的癫痫发作类型（n = 22），平均癫痫发作持续时间为 49.50 个月（SD + 31.04 个月）。最常见的病理是神经胶质瘤（GNT）（n = 17）。与次全切除 (STR) 组相比，大体全切除 (GTR) 组的癫痫发作结果明显更好 (p = 0.006)。局灶性或部分性癫痫的存在是指向更好的癫痫控制的重要因素（p = 0.005）。结论 较短的症状持续时间、部分/局部癫痫发作和总切除是良好癫痫发作结果的预测因素。在比较 GNT 与非 GNT 时，患者的年龄和肿瘤的组织病理学不影响癫痫发作结果。