This study investigated the combined impact of sauerkraut and Leuconostoc mesenteroides culture on immunomodulatory activity in experimental animal. The in vivo immunomodulatory activity of Escherichia coli-infected Balb-C mice was ascertained in fermented sauerkrauts [test vs. control]. Both sauerkrauts enhanced the adaptive immune response [evidenced by an increase in CD4⁺ CD8⁺ IFN-γ, TNFα] and innate immune response [represented by a decrease of CD68-IL-6]. Nevertheless, the in vivo immunomodulatory activity of sauerkraut combined with L. mesenteroides was higher than that shown in sauerkraut control solely.

中文翻译：

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酸菜与猪肠球菌的联合作用增强了大肠杆菌感染小鼠的免疫调节活性

这项研究调查了德国泡菜和肠膜亮粉对培养动物免疫调节活性的综合影响。在发酵的酸菜中确定了大肠杆菌感染的Balb-C小鼠的体内免疫调节活性[测试与对照]。两种德国泡菜都增强了适应性免疫反应（以CD4 ⁺ CD8 ⁺ IFN-γ，TNFα的增加为证据）和先天免疫反应（以CD68-IL-6的减少为代表）。然而，酸菜与肠系膜乳杆菌联合的体内免疫调节活性高于仅酸菜对照中显示的免疫调节活性。