Abstract

The use of animal models in Parkinson’s disease research has been controversial in terms of how well they relate to the clinical condition and thus their utility for translating therapies from the lab to the clinic. In this article, two researchers debate this issue with Roger Barker taking the view that such models are not useful and may even be misleading, while Anders Björklund defends their use and highlights their value in better understanding and treating this condition.

中文翻译：

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帕金森病的动物模型：它们有用还是没有用？

摘要

在帕金森病研究中使用动物模型一直存在争议，因为它们与临床状况的关系以及它们将疗法从实验室转化为临床的效用。在这篇文章中，两名研究人员与 Roger Barker 讨论了这个问题，他们认为这些模型没有用，甚至可能会产生误导，而 Anders Björklund 捍卫它们的使用并强调它们在更好地理解和治疗这种情况方面的价值。