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Review of Serum Biomarkers and Models Derived from Them in HBV-Related Liver Diseases.
Disease Markers Pub Date : 2020-07-21 , DOI: 10.1155/2020/2471252
JianPing Wu 1 , WeiLin Mao 1
Affiliation  

A series of predictive scoring systems is available for stratifying the severity of conditions and assessing the prognosis in patients with HBV-related liver diseases. We show nine of the most popular serum biomarkers and their models (i.e., serum cystatin C, homocysteine, C-reactive protein, C-reactive protein to albumin ratio, aspartate aminotransferase to platelet ratio index, fibrosis index based on four factors, gamma-glutamyl transpeptidase to platelet ratio, albumin-bilirubin score, and gamma-glutamyl transpeptidase to albumin ratio) that have gained great interest from clinicians. Compared with traditional scoring systems, these serum biomarkers and their models are easily acquired, simple, and relatively inexpensive. In the present review, we summarize the latest studies focused on these serum biomarkers and their models as diagnostic and prognostic indexes in HBV-related liver diseases.

中文翻译:

HBV相关肝病患者血清生物标志物和模型的回顾。

一系列预测评分系统可用于对病情的严重程度进行分层并评估HBV相关肝病患者的预后。我们展示了九种最受欢迎​​的血清生物标志物及其模型(即,血清胱抑素C,高半胱氨酸,C反应蛋白,C反应蛋白与白蛋白的比率,天冬氨酸转氨酶与血小板的比率指数,基于四个因素的纤维化指数,γ-谷氨酰转肽酶与血小板的比率,白蛋白-胆红素评分和γ-谷氨酰转肽酶与白蛋白的比率)引起了临床医生的极大兴趣。与传统评分系统相比,这些血清生物标志物及其模型易于获得,简单且相对便宜。在目前的评论中,
更新日期:2020-07-22
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