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Heritability Estimates of Antler and Body Traits in White-Tailed Deer (Odocoileus virginianus) From Genomic-Relatedness Matrices
Journal of Heredity ( IF 3.0 ) Pub Date : 2020-07-01 , DOI: 10.1093/jhered/esaa023
Aidan Jamieson 1 , Spencer J Anderson 2 , Jérémie Fuller 3 , Steeve D Côté 3 , Joseph M Northrup 2, 4 , Aaron B A Shafer 2, 5
Affiliation  

Estimating heritability (h2) is required to predict the response to selection and is useful in species that are managed or farmed using trait information. Estimating h2 in free-ranging populations is challenging due to the need for pedigrees; genomic-relatedness matrices (GRMs) circumvent this need and can be implemented in nearly any system where phenotypic and genome-wide single nucleotide polymorphism (SNP) data are available. We estimated the heritability of five body and three antler traits in a free-ranging population of white-tailed deer (Odocoileus virginianus) on Anticosti Island, Quebec, Canada. We generated classic and robust GRMs from >10,000 SNPs: hind foot length, dressed body mass and peroneus muscle mass had high h2 values of 0.62, 0.44 and 0.55, respectively. Heritability in male-only antler features ranged from 0.07 to 0.33 and had high standard errors. We explored the influence of filtering by minor allele frequency and data completion on h2: GRMs derived from fewer SNPs had reduced h2 estimates and the relatedness coefficients significantly deviated from those generated with more SNPs. As a corollary, we discussed limitations to the application of GRMs in the wild, notably how skewed GRMs, specifically many unrelated individuals, can increase variance around h2 estimates. This is the first study to estimate h2 on a free-ranging population of white-tailed deer and should be informative for breeding designs and management as these traits should respond to selection.

中文翻译:

从基因组相关矩阵估计白尾鹿 (Odocoileus virginianus) 鹿角和身体特征的遗传力

需要估计遗传力 (h2) 来预测对选择的反应,并且在使用性状信息管理或养殖的物种中很有用。由于需要谱系,估计自由放养种群的 h2 具有挑战性;基因组相关性矩阵 (GRM) 绕过了这种需求,并且几乎可以在任何可以获得表型和全基因组单核苷酸多态性 (SNP) 数据的系统中实施。我们估计了加拿大魁北克安蒂科斯蒂岛白尾鹿(Odocoileus virginianus)自由放养种群的五种身体特征和三种鹿角特征的遗传力。我们从超过 10,000 个 SNP 生成经典和强大的 GRM:后足长度、穿着体重和腓骨肌肉质量分别具有 0.62、0.44 和 0.55 的高 h2 值。仅雄性鹿角特征的遗传力从 0.07 到 0 不等。33 并且具有高标准误差。我们探讨了通过次要等位基因频率和数据完成过滤对 h2 的影响:源自较少 SNP 的 GRM 降低了 h2 估计值,并且相关系数显着偏离了较多 SNP 产生的系数。作为推论,我们讨论了在野外应用 GRM 的局限性,特别是倾斜的 GRM,特别是许多不相关的个​​体,如何增加 h2 估计值的方差。这是第一项估计自由放养白尾鹿种群 h2 的研究,应该为育种设计和管理提供信息,因为这些性状应该对选择做出反应。源自较少 SNP 的 GRM 降低了 h2 估计值,并且相关系数显着偏离了较多 SNP 产生的系数。作为推论,我们讨论了在野外应用 GRM 的局限性,特别是倾斜的 GRM,特别是许多不相关的个​​体,如何增加 h2 估计值的方差。这是第一项估计自由放养白尾鹿种群 h2 的研究,应该为育种设计和管理提供信息,因为这些性状应该对选择做出反应。源自较少 SNP 的 GRM 降低了 h2 估计值,并且相关系数显着偏离了较多 SNP 产生的系数。作为推论,我们讨论了在野外应用 GRM 的局限性,特别是倾斜的 GRM,特别是许多不相关的个​​体,如何增加 h2 估计值的方差。这是第一项估计自由放养白尾鹿种群 h2 的研究,应该为育种设计和管理提供信息,因为这些性状应该对选择做出反应。
更新日期:2020-07-01
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