Abstract

The new compound totaiol (isolated from Acrocomia totai) was misnamed as a hopane-type triterpene. Considering its biosynthesis, it could be considered as an intermediate of other triterpenes isolated from the same source (following a sterol folding of 2,3-squalene oxide). In contrast, hopane-type triterpenes follow a different biosynthetic route (non-sterol folding of 2,3-squalene oxide). The stereochemical and substitutional array trans, syn, trans, anti, trans, anti, trans for the A-E rings of the triterpene totaiol (1) is not known, and therefore, its biosynthetic significance as an important intermediate should be emphasized. This new group of triterpenic skeletons could be named totaianes.

摘要

新化合物 totaiol（从Acrocomia totai中分离）被错误命名为藿烷型三萜。考虑到它的生物合成，它可以被认为是从同一来源分离的其他三萜的中间体（在 2,3-氧化角鲨烯的甾醇折叠之后）。相反，藿烷型三萜遵循不同的生物合成路线（2,3-氧化角鲨烯的非甾醇折叠）。立体化学和取代阵列trans , syn , trans , anti , trans , anti , trans代表三萜烯妥泰醇的 AE 环 ( 1) 未知，因此应强调其作为重要中间体的生物合成意义。这组新的三萜骨架可以被命名为totaianes。