Direct analysis of chemicals on a surface using mass spectrometry (MS) is of great importance in forensics, food and drug safety, environmental monitoring, and defense. Solvent extraction–based surface analysis offers a convenient way of controlling the desorption conditions and applying internal standards. To date, it mainly relies on a separate electrospray process to nebulize and ionize the solvents. Here, we report a simple and stand‐alone ionization system for the solvent extraction–based surface analysis without the need for high voltage, based on vibrating sharp‐edge spray ionization (VSSI).

中文翻译：

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使用振动锐边喷雾电离质谱法直接分析表面化学物质。

使用质谱法 (MS) 直接分析表面上的化学物质在法医学、食品和药物安全、环境监测和防御中具有重要意义。基于溶剂萃取的表面分析提供了一种控制解吸条件和应用内标的便捷方法。迄今为止，它主要依靠单独的电喷雾过程来雾化和电离溶剂。在这里，我们报告了一种基于振动锐边喷雾电离 (VSSI) 的简单且独立的电离系统，用于基于溶剂萃取的表面分析，无需高电压。