Evaluation of interactive effects between paternal alcohol consumption and paternal socioeconomic status and environmental exposures on congenital heart defects.,Birth Defects Research

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Evaluation of interactive effects between paternal alcohol consumption and paternal socioeconomic status and environmental exposures on congenital heart defects.
Birth Defects Research ( IF 1.6 ) Pub Date : 2020-07-21 , DOI: 10.1002/bdr2.1759
Zhiqiang Nie ₁ , Yanji Qu ₁ , Fengzhen Han ₂ , Erin M Bell _{3,

4} , Jian Zhuang ₅ , Jimei Chen ₅ , Melissa François _{3,

4} , Emily Lipton _{3,

4} , Rosemary Matale _{3,

4} , Weilun Cui ₆ , Qianhong Liang ₇ , Xiangzhang Lu ₈ , Huiwen Huang ₉ , Junfeng Lv ₁₀ , Yanqiu Ou ₁ , Jinzhuang Mai ₁ , Yong Wu ₁ , Xiangmin Gao ₁ , Yating Huang ₁ , Shao Lin _{3,

4} , Xiaoqing Liu ₁

Affiliation

Department of Epidemiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Department of Obstetrics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Department of Environmental Health Sciences, University at Albany, State University of New York, Albany, New York, USA.
Department of Epidemiology and Biostatistics, University at Albany, State University of New York, Albany, New York, USA.
Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Department of Neonatology, Panyu General Hospital, Guangzhou, Guangdong, China.
Department of Echocardiography, Panyu Maternal and Child Care Service Centre, Guangzhou, Guangdong, China.
Department of Echocardiography, Huadu Maternal and Child Care Service Centre, Guangzhou, Guangdong, China.
Department of Neonatology, Zhuhai Maternal and Child Care Service Center, Zhuhai, Guangdong, China.
Department of Neonatology, Boai Hospital of Zhongshan, Zhongshan, Guangdong, China.

While the maternal risk factors on congenital heart defects (CHDs) have often been assessed, paternal contribution to CHDs, especially the joint effects of paternal risk factors on CHDs remain unknown. This study examined the major impacts of paternal alcohol consumption and its interaction (on multiplicative and additive scales) with paternal socioeconomic status (SES) and environmental exposures on CHDs in China.

更新日期：2020-07-21

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