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Effect of stimulation sites on the performance of electromagnetic middle ear implant: A finite element analysis.
Computers in Biology and Medicine ( IF 7.0 ) Pub Date : 2020-07-22 , DOI: 10.1016/j.compbiomed.2020.103918
Houguang Liu 1 , Wenbo Wang 1 , Yu Zhao 1 , Jianhua Yang 1 , Shanguo Yang 1 , Xinsheng Huang 2 , Wen Liu 3
Affiliation  

Electromagnetic middle ear implants (MEIs), which use the mechanical vibration of their implanted transducers to treat hearing loss, have emerged to overcome the limitations of conventional hearing aids. Several reports have indicated that the electromagnetic MEI's performance changed with different stimulation sites of the transducer. The aim of this study was to analyze the influence of the transducers' stimulation sites on the electromagnetic MEIs' performance. To aid this investigation, a human ear finite-element model was developed from micro-CT images of an adult's right ear. The validity of the model was confirmed by comparing the model-derived results with experimental data. Then, stimulation forces, which simulate ideal electromagnetic transducers, were respectively applied at five typical coupling sites: the umbo, incus body, incus long process, the round window, and the stapes. The stimulation sites' influence on the electromagnetic MEI's performance was studied by analyzing their corresponding basilar membrane displacements. The results show that stimulation of the round window with a force produces more cochlear stimulation than equal force stimulation of the umbo, incus body, incus long process and the stapes, though the superiority of the round window depends on its smaller area compared to the stapes footplate. Among the forward stimulation, the stapes is the optimal stimulation site for the electromagnetic transducer regarding its hearing compensation's efficiency. The performance of the umbo stimulation is comparable to that of the incus-long-process stimulation. Driving the incus body is less efficient than stimulating the other forward driving sites. Additional, using the stapes response to evaluate the forward stimulation gives results similar to those deduced by the basilar membrane response; in contrast, for the round-window stimulation, the evaluation result based on the stapes response is prominently less than the one calculated by the basilar membrane response, especially in the mid-high frequency range.



中文翻译:

刺激部位对电磁中耳植入物性能的影响:有限元分析。

为了克服传统助听器的局限性,已经出现了电磁中耳植入物(MEI),该植入物利用其植入的换能器的机械振动来治疗听力损失。几份报告表明,电磁MEI的性能随换能器的不同刺激部位而变化。这项研究的目的是分析换能器的刺激部位对电磁MEI性能的影响。为了帮助进行这项研究,从成年人的右耳的微型CT图像中开发了人耳有限元模型。通过将模型得出的结果与实验数据进行比较,可以确认模型的有效性。然后,将模拟理想电磁换能器的刺激力分别施加到五个典型的耦合位置:超音波,骨的身体,in骨的长进程,圆形的窗口和the骨。通过分析其相应的基底膜位移,研究了刺激部位对电磁MEI性能的影响。结果表明,用力刺激圆形窗比用相同的力刺激腰鼓,in骨,in骨长突和the骨可产生更多的耳蜗刺激,尽管圆形窗的优越性取决于与the骨相比面积较小踏板。就正向刺激而言,就其听力补偿的效率而言,骨是电磁换能器的最佳刺激部位。umbo刺激的性能与incus-long-process刺激的性能相当。驾驶in肌比刺激其他向前驾驶部位效率低。另外,使用the骨反应评估前向刺激得到的结果与基底膜反应推论的结果相似。相反,对于圆形窗口刺激,基于sta骨响应的评估结果明显少于通过基底膜响应计算的评估结果,尤其是在中高频范围内。

更新日期:2020-08-03
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