Polyimides and their modified forms (e.g., poly(imide-siloxanes)) are an important class of unique polymers. Their typical two-step preparation includes the preparation of a solution of the polyimide precursor in an amidic solvent (e.g., N-methyl-2-pyrrolidone, N,N-dimethylacetamide). Currently, these solvents are classified as toxic, and there is a strong demand to limit their use. Therefore, this study addresses the preparation of polyimides by nontoxic γ-butyrolactone as a solvent and the synthesis of polyimides and poly(imide-siloxanes) in the presence of an enzyme without the use of a solvent. The ability of these products to form self-standing films (membranes) and their thermal and mechanical properties have been found, at least partly, to be comparable to those of the products prepared by using traditional amidic solvents.

Chemoenzymatic Preparation of Poly(imide-siloxane) without Use any Solvent.

聚酰亚胺及其改性形式（例如，聚（酰亚胺-硅氧烷））是一类重要的独特聚合物。他们典型的两步制备包括制备聚酰亚胺前体在酰胺溶剂中的溶液（例如，N-甲基-2-吡咯烷酮，N，N-二甲基乙酰胺）。当前，这些溶剂被分类为有毒的，并且强烈要求限制其使用。因此，本研究致力于通过无毒的γ-丁内酯作为溶剂制备聚酰亚胺，以及在不使用溶剂的情况下在酶的存在下合成聚酰亚胺和聚（酰亚胺-硅氧烷）。已经发现这些产品形成自立膜（膜）的能力及其热和机械性能至少部分地与使用传统酰胺溶剂制备的产品相当。

不使用任何溶剂的化学酶法制备聚（酰亚胺-硅氧烷）的方法。