The advent of technologies such as magnetic resonance imaging (MRI)-guided radiation therapy has led to the need for phantom materials that are capable of producing tissue-like contrast on both MRI and computed tomography (CT) imaging modalities. The purpose of this work is to develop a system of easily made and formed materials with adjustable T 1 and T 2 relaxation times, and x-ray attenuation properties, for mimicking soft tissue and bone with both MRI and CT imaging modalities. The effects on T 1 /T 2 relaxation times and CT numbers were quantified for a range of gadolinium contrast (0–25 μ mol g -1 ), agarose (0%–8% w/w), glass microspheres (0%–10% w/w) and CaCO 3 (0%–50% w/w) concentrations in a carrageenan-based gel. 105 gel samples were prepared with the additives, carrageenan and water. Samples were imaged in a 3D-printed holding structure to find the attainable range of T 1 /T 2 relaxati...

中文翻译：

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用于计算机断层扫描和磁共振成像的组织模仿材料的通用系统。

诸如磁共振成像（MRI）引导的放射疗法等技术的出现导致了对幻象材料的需求，这些幻象材料能够在MRI和计算机断层摄影（CT）成像方式上产生类似组织的对比度。这项工作的目的是开发一种易于制造和成型的材料系统，该系统具有可调节的T 1和T 2弛豫时间以及X射线衰减特性，可通过MRI和CT成像方式模拟软组织和骨骼。在一定范围的contrast对比（0–25μmol g -1），琼脂糖（0％–8％w / w），玻璃微球（0％–角叉菜胶凝胶中浓度为10％w / w和CaCO 3（0％–50％w / w）。用添加剂，角叉菜胶和水制备了105个凝胶样品。