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Metagenomic insights into the effects of nanobubble water on the composition of gut microbiota in mice.
Food & Function ( IF 5.1 ) Pub Date : 2020-07-21 , DOI: 10.1039/d0fo01592j Zitao Guo 1 , Bo Hu , Hanlin Han , Zhongfang Lei , Kazuya Shimizu , Liang Zhang , Zhenya Zhang
Food & Function ( IF 5.1 ) Pub Date : 2020-07-21 , DOI: 10.1039/d0fo01592j Zitao Guo 1 , Bo Hu , Hanlin Han , Zhongfang Lei , Kazuya Shimizu , Liang Zhang , Zhenya Zhang
Affiliation
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The particular physicochemical and biological properties of nanobubbles (NBs) have prompted many researchers to conduct an in-depth study on their potential application in various fields. This study aims to investigate the effects of nanobubble water (NBW) on the community structure of the gut microbiota in mice. In this study, supplementation with nitrogen NBW (SD-N2 group), hydrogen NBW (SD-H2 group) and deionized water (SD-C group) to a standard diet of mice was performed for five weeks. The composition of fecal microbiota was analyzed by using 16S rRNA gene sequencing. Compared with the SD-C group, the species diversity of the fecal microbiota in mice in NBW groups was significantly increased. At the genus level, supplementation with nitrogen NBW to mice significantly increased the relative abundance of two beneficial genera Clostridium and Coprococcus (mean growth 6.3 times and 9.7 times, respectively), while supplementation with hydrogen NBW significantly decreased the relative abundance of two pathogenic genera Mucispirillum and Helicobacter (mean reduction rate 86% and 60%, respectively). These results demonstrate that supplementation with NBW might optimize the composition of gut microbiota in mice.
中文翻译：
纳米气泡水对小鼠肠道菌群组成影响的元基因组学见解。
纳米气泡（NBs）的特殊物理化学和生物学特性促使许多研究人员对其在各个领域的潜在应用进行了深入研究。这项研究旨在调查纳米气泡水（NBW）对小鼠肠道菌群的群落结构的影响。在这项研究中，补充了氮NBW（SD-N 2组），氢NBW（SD-H 2组）组）和去离子水（SD-C组）对小鼠的标准饮食进行了五周。通过使用16S rRNA基因测序分析粪便微生物群的组成。与SD-C组相比，NBW组小鼠粪便微生物群的物种多样性明显增加。在属水平上，向小鼠补充氮NBW显着增加了两个有益梭菌属和协球菌属的相对丰度（分别增长了6.3倍和9.7倍），而向氢气补充NBW显着降低了两个致病菌粘螺旋藻的相对丰度和幽门螺杆菌（平均减少率分别为86％和60％）。这些结果表明，补充NBW可能会优化小鼠肠道菌群的组成。
更新日期：2020-08-19
中文翻译：
纳米气泡水对小鼠肠道菌群组成影响的元基因组学见解。
纳米气泡（NBs）的特殊物理化学和生物学特性促使许多研究人员对其在各个领域的潜在应用进行了深入研究。这项研究旨在调查纳米气泡水（NBW）对小鼠肠道菌群的群落结构的影响。在这项研究中，补充了氮NBW（SD-N 2组），氢NBW（SD-H 2组）组）和去离子水（SD-C组）对小鼠的标准饮食进行了五周。通过使用16S rRNA基因测序分析粪便微生物群的组成。与SD-C组相比，NBW组小鼠粪便微生物群的物种多样性明显增加。在属水平上，向小鼠补充氮NBW显着增加了两个有益梭菌属和协球菌属的相对丰度（分别增长了6.3倍和9.7倍），而向氢气补充NBW显着降低了两个致病菌粘螺旋藻的相对丰度和幽门螺杆菌（平均减少率分别为86％和60％）。这些结果表明，补充NBW可能会优化小鼠肠道菌群的组成。
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