Loading‐induced tension development is often assumed to constitute an independent cue to initiate muscle protein synthesis following resistance exercise. However, with traditional physiological models of resistance exercise, changes in loading‐induced tension development also reflect changes in neural activation patterns, and direct evidence for a mechanosensitive mechanism is therefore limited. Here, we sought to examine the importance of excitation and tension development per se on initiation of signalling, gene transcription and protein synthesis in rat skeletal muscle.

中文翻译：

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大鼠骨骼肌中的肌细胞基因表达和蛋白质合成需要伴随的兴奋和张力发展。

负荷引起的张力发展通常被认为是在阻力运动后启动肌肉蛋白质合成的独立线索。然而，在传统的抗阻运动生理模型中，负荷引起的张力发展的变化也反映了神经激活模式的变化，因此机械敏感性机制的直接证据是有限的。在这里，我们试图检查激发和张力发展本身对大鼠骨骼肌中信号传导、基因转录和蛋白质合成的重要性。