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Hypoglycemic and antioxidant effects of five commercial turmeric (Curcuma longa) supplements.
Journal of Food Biochemistry ( IF 3.5 ) Pub Date : 2020-07-21 , DOI: 10.1111/jfbc.13389 Fernando Guerrero-Romero 1 , Luis E Simental-Mendía 1 , Gerardo Martínez-Aguilar 1 , Miguel A Sánchez-Meraz 1 , Claudia I Gamboa-Gómez 1
Journal of Food Biochemistry ( IF 3.5 ) Pub Date : 2020-07-21 , DOI: 10.1111/jfbc.13389 Fernando Guerrero-Romero 1 , Luis E Simental-Mendía 1 , Gerardo Martínez-Aguilar 1 , Miguel A Sánchez-Meraz 1 , Claudia I Gamboa-Gómez 1
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We evaluate the hypoglycemic and antioxidant effects of five commercial turmeric (Curcuma longa) supplements: (1) bulk samples, (2) turmeric root from India, (3) curcuma turmeric Pronat®, (4) turmeric & black pepper Swanson®, and (5) C3 complex® turmeric curcumin. Glucose diffusion and enzymatic starch digestion assays, using α‐amylase and α‐glucosidase, were performed. The antioxidant activity of turmeric supplements was measured through lipid peroxidation inhibition and the scavenging radical assay. A starch dose of 102 mg/Kg of body weight (equivalent to 1 g/day in humans) was used to perform the oral starch tolerance test (OSTT) in Wistar male rats. All turmeric supplements decreased glucose diffusion and α‐glucosidase enzyme activity, and inhibited lipid peroxidation. The rats that received bulk samples and CT showed significantly lower glucose levels than rats receiving acarbose and those of negative control group. Our results show that biological activities of turmeric supplements vary according to the commercial presentation.
中文翻译：
五种商业姜黄（姜黄）的降血糖和抗氧化作用。
我们评估五大商业姜黄（降血糖和抗氧化作用姜黄）补充：（1）散装样品，（2）来自印度姜黄根，（3）姜黄姜黄Pronat ®，（4），姜黄和黑胡椒斯旺森®，以及（5）C3复合物®姜黄姜黄素。使用α-淀粉酶和α-葡萄糖苷酶进行了葡萄糖扩散和酶促淀粉消化测定。姜黄补充剂的抗氧化活性通过脂质过氧化抑制作用和清除自由基试验进行测定。将102毫克/千克体重的淀粉剂量（相当于人类1克/天）用于Wistar雄性大鼠的口服淀粉耐受性测试（OSTT）。所有姜黄补充剂均会降低葡萄糖扩散和α-葡萄糖苷酶活性，并抑制脂质过氧化。接受大量样品和CT的大鼠的葡萄糖水平显着低于接受阿卡波糖和阴性对照组的大鼠。我们的结果表明，姜黄补充剂的生物学活性根据商业用途而有所不同。
更新日期：2020-09-14
中文翻译：
五种商业姜黄（姜黄）的降血糖和抗氧化作用。
我们评估五大商业姜黄（降血糖和抗氧化作用姜黄）补充：（1）散装样品，（2）来自印度姜黄根，（3）姜黄姜黄Pronat ®，（4），姜黄和黑胡椒斯旺森®，以及（5）C3复合物®姜黄姜黄素。使用α-淀粉酶和α-葡萄糖苷酶进行了葡萄糖扩散和酶促淀粉消化测定。姜黄补充剂的抗氧化活性通过脂质过氧化抑制作用和清除自由基试验进行测定。将102毫克/千克体重的淀粉剂量（相当于人类1克/天）用于Wistar雄性大鼠的口服淀粉耐受性测试（OSTT）。所有姜黄补充剂均会降低葡萄糖扩散和α-葡萄糖苷酶活性，并抑制脂质过氧化。接受大量样品和CT的大鼠的葡萄糖水平显着低于接受阿卡波糖和阴性对照组的大鼠。我们的结果表明，姜黄补充剂的生物学活性根据商业用途而有所不同。
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