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Comparative genomics and transcriptomics of 4 Paragonimus species provide insights into lung fluke parasitism and pathogenesis.
GigaScience ( IF 9.2 ) Pub Date : 2020-07-20 , DOI: 10.1093/gigascience/giaa073
Bruce A Rosa 1 , Young-Jun Choi 1 , Samantha N McNulty 2 , Hyeim Jung 1 , John Martin 1 , Takeshi Agatsuma 3 , Hiromu Sugiyama 4 , Thanh Hoa Le 5 , Pham Ngoc Doanh 6, 7 , Wanchai Maleewong 8, 9 , David Blair 10 , Paul J Brindley 11 , Peter U Fischer 1 , Makedonka Mitreva 1, 2
Affiliation  

Paragonimus spp. (lung flukes) are among the most injurious foodborne helminths, infecting ∼23 million people and subjecting ∼292 million to infection risk. Paragonimiasis is acquired from infected undercooked crustaceans and primarily affects the lungs but often causes lesions elsewhere including the brain. The disease is easily mistaken for tuberculosis owing to similar pulmonary symptoms, and accordingly, diagnostics are in demand.

中文翻译:

4 种肺吸虫的比较基因组学和转录组学提供了对肺吸虫寄生和发病机制的见解。

并殖吸虫属 (肺吸虫)是危害最大的食源性蠕虫之一,感染约 2300 万人并使约 2.92 亿人面临感染风险。肺吸虫病是从受感染的未煮熟的甲壳类动物中获得的,主要影响肺部,但通常会在包括大脑在内的其他部位引起病变。由于类似的肺部症状,这种疾病很容易被误认为是肺结核,因此需要进行诊断。
更新日期:2020-07-20
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