Combining statistical shape modeling, CFD, and meta-modeling to approximate the patient-specific pressure-drop across the aortic valve in real-time.,International Journal for Numerical Methods in Biomedical Engineering

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Combining statistical shape modeling, CFD, and meta-modeling to approximate the patient-specific pressure-drop across the aortic valve in real-time.
International Journal for Numerical Methods in Biomedical Engineering ( IF 2.2 ) Pub Date : 2020-07-20 , DOI: 10.1002/cnm.3387
M J M M Hoeijmakers _{1,

2} , I Waechter-Stehle ₃ , J Weese ₃ , F N Van de Vosse ₁

Affiliation

Advances in medical imaging, segmentation techniques, and high performance computing have stimulated the use of complex, patient‐specific, three‐dimensional Computational Fluid Dynamics (CFD) simulations. Patient‐specific, CFD‐compatible geometries of the aortic valve are readily obtained. CFD can then be used to obtain the patient‐specific pressure‐flow relationship of the aortic valve. However, such CFD simulations are computationally expensive, and real‐time alternatives are desired.

中文翻译：

结合统计形状建模、CFD 和元建模，实时近似跨主动脉瓣的患者特定压降。

医学成像、分割技术和高性能计算的进步刺激了复杂的、特定于患者的、三维计算流体动力学 (CFD) 模拟的使用。很容易获得患者特定的、与 CFD 兼容的主动脉瓣几何形状。然后可以使用 CFD 来获得患者特定的主动脉瓣压力-流量关系。然而，这种 CFD 模拟的计算成本很高，需要实时替代方案。

更新日期：2020-07-20

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