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Oxidative cross-coupling approach to the biomimetic synthesis of the heterodimers of resveratrol and isorhapontigenin
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-07-20 , DOI: 10.1016/j.tetlet.2020.152239
Hongpeng Li , Lu Ran , Meijie Liu , Tian Lei , Xiaodong Kang , Wenling Li

The regioselective oxidative cross-coupling reactions of two different stilbene precursors catalyzed by FeCl3 or horseradish peroxidase-H2O2 in acetone solvent produced three dihydrobenzofuran-type heterodimers. The reductive debrominations of these cross-coupled dimers synthesized two heterodimers of resveratrol and isorhapontigenin, an analogue of (±)-scirpusin A and (±)-gnetuhainin Q.



中文翻译:

氧化交叉偶联法仿生合成白藜芦醇和异皂甙元的异二聚体

FeCl 3或辣根过氧化物酶-H 2 O 2在丙酮溶剂中催化的两种不同的二苯乙烯前体的区域选择性氧化交叉偶联反应产生了三种二氢苯并呋喃型异二聚体。这些交叉偶联的二聚体的还原脱溴反应合成了白藜芦醇和异皂甙元的两个异二聚体,这是(±)-scirpusin A和(±)-gnetuhainin Q的类似物。

更新日期:2020-08-06
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