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Endothelial Cells Don't Waste: Endothelial-Derived Lactate Boosts Muscle Regeneration.
Developmental Cell ( IF 10.7 ) Pub Date : 2020-07-20 , DOI: 10.1016/j.devcel.2020.06.023
Marco Castro 1 , Jorge Andrade 1 , Michael Potente 2
Affiliation  

Blood vessels are an essential interface between the circulation and tissue that deploy signaling molecules (angiocrines) for organ development, homeostasis, and repair. In a recent issue of Cell Metabolism, Zhang et al. (2020) identify lactate as an endothelial-derived signal promoting ischemic muscle regeneration, establishing metabolites as a new angiocrine class.



中文翻译:

内皮细胞不浪费:内皮源性乳酸促进肌肉再生。

血管是循环系统与组织之间的重要接口,这些接口部署信号分子(血管内分泌)进行器官发育,体内平衡和修复。在最近一期《细胞代谢》一书中,Zhang等人。(2020)确定乳酸为内皮细胞信号,促进缺血性肌肉再生,建立代谢产物为新的血管分泌类别。

更新日期:2020-07-20
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