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Nutrients men-TOR β-Cells to Adulthood.
Developmental Cell ( IF 10.7 ) Pub Date : 2020-07-20 , DOI: 10.1016/j.devcel.2020.06.028
Keiichi Katsumoto 1 , Anne Grapin-Botton 2
Affiliation  

A major trigger of adult β-cell insulin secretion is glucose. In a recent issue of Cell Metabolism, Helman and colleagues show that in fetuses insulin secretion depends on the activation of mTOR by amino acids and that reducing amino acids promotes maturation of β-cells derived from pluripotent stem cells.



中文翻译:

营养物质的人-TORβ细胞到成年。

成人β细胞胰岛素分泌的主要触发因素是葡萄糖。在最新一期的《细胞代谢》中,Helman及其同事表明,在胎儿中,胰岛素的分泌取决于氨基酸对mTOR的激活,而减少氨基酸可促进多能干细胞衍生的β细胞成熟。

更新日期:2020-07-20
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