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Thermomagnetic resonance affects cancer growth and motility.
Royal Society Open Science ( IF 2.9 ) Pub Date : 2020-07-15 , DOI: 10.1098/rsos.200299
Umberto Lucia 1 , Giulia Grisolia 1 , Antonio Ponzetto 2 , Loredana Bergandi 3 , Francesca Silvagno 3
Affiliation  

The fight against a multifaceted incurable disease such as cancer requires a multidisciplinary approach to overcome the multitude of molecular defects at its origin. Here, a new thermophysical biochemical approach has been suggested and associated with the use of electromagnetic fields to control the growth of cancer cells. In particular, thermodynamic analysis of the heat transfer is developed in correlation with cellular parameters such as the volume/area ratio. We propose that the electromagnetic wave, at the specific frequency calculated as the characteristic response time of any cell type to the external thermal perturbation, can affect resonant intracellular molecular oscillations. The biochemical model hypothesizes that microtubules are stabilized, and the impact is predicted on cell growth, migration and mitochondrial activity. Experimental validation of the theoretical results shows that the thermodynamic analysis allows the application of the specific electromagnetic field able to decrease cancer cell invasion and proliferation.



中文翻译:

热磁共振影响癌症的生长和运动。

与多方面的不可治愈的疾病(例如癌症)的斗争需要采取多学科的方法来克服其起源上的众多分子缺陷。在这里,已经提出了一种新的热物理生化方法,并与电磁场的使用相关联以控制癌细胞的生长。特别地,与诸如体积/面积比之类的细胞参数相关联地开发了热传递的热力学分析。我们建议以特定频率计算的电磁波作为任何细胞类型对外部热扰动的特征响应时间,可以影响共振的细胞内分子振荡。生化模型假设微管是稳定的,并且可以预测其对细胞生长,迁移和线粒体活性的影响。

更新日期:2020-07-20
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