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The Relationship between HDAC3 and Malignant Tumors: A Mini Review.
Critical Reviews in Eukaryotic Gene Expression ( IF 1.5 ) Pub Date : 2020-01-01 , DOI: 10.1615/critreveukaryotgeneexpr.2020034380
Lou Tong 1 , Haotian Liang 2 , Huiyu Zhuang 2 , Chongdong Liu 1 , Zhenyu Zhang 1
Affiliation  

Histone deacetylases 3 (HDAC3) is a member of the histone deacetylases family. This family is associated with cellular physiological function, such as signal transduction, cell cycle, proliferation, apoptosis, and cardiac development. HDAC3 plays an important role in the progression of malignant tumors, especially in terms of proliferation, apoptosis, metastasis, angiogenesis, and anticancer drug resistance. This review discusses the basic elements of HDAC3 and the relationship between HDAC3 and malignant tumors.

中文翻译:

HDAC3与恶性肿瘤之间的关系:迷你审查。

组蛋白脱乙酰基酶3(HDAC3)是组蛋白脱乙酰基酶家族的成员。该家族与细胞生理功能有关,例如信号转导,细胞周期,增殖,凋亡和心脏发育。HDAC3在恶性肿瘤的进展中起着重要作用,尤其是在增殖,凋亡,转移,血管生成和抗癌药物耐药性方面。这篇综述讨论了HDAC3的基本成分以及HDAC3与恶性肿瘤之间的关系。
更新日期:2020-01-01
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