In the present study, the antioxidant, antimicrobial potential and antiproliferative activity of Lactifluus rugatus mushroom were determined. Thus, extracts of the mushroom were obtained using a Soxhlet device. Antioxidant and oxidant potentials were determined using Rel Assay kits. Antimicrobial potential was tested on 9 microorganisms using the modified agar dilution method. MTT test was conducted on A549 cells to determine the anti-proliferative activity. As a result, high level of antioxidant activity was determined in L. rugatus. Furthermore, it was determined that the mushroom had antimicrobial properties on tested bacteria and fungi and strong anti-proliferative activity on A549 cells. In conclusion, it was considered that L. rugatus had pharmacological potential and it can be utilized as a natural pharmacological agent.


中文翻译：

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皱纹乳杆菌的抗氧化和抗菌能力及其对A549细胞的增殖活性

在本研究中，测定了皱叶乳杆菌蘑菇的抗氧化剂，抗菌潜力和抗增殖活性。因此，使用索氏提取器获得蘑菇的提取物。使用Rel Assay试剂盒测定抗氧化剂和氧化剂的潜力。使用改良的琼脂稀释法对9种微生物进行了抗菌潜力测试。对A549细胞进行MTT测试以确定抗增殖活性。结果，在皱叶乳杆菌中确定了高水平的抗氧化剂活性。此外，已确定蘑菇对测试的细菌和真菌具有抗菌性能，并且对A549细胞具有很强的抗增殖活性。总之，认为皱褶乳杆菌具有药理潜力，可以用作天然药理剂。