The purpose of this paper is a new thin-film based sensor proposed for sensitive and selective detection of mercury (Hg2+) ions in water. The thin-film platform is easy to use and quick for heavy metal ions (HMIs) detection in the picomolar range. Ion-selective self-assembled monolayer's (SAM) of thiol used for the detection of HMIs above the Au/Ti top surface.,A thin-film based platform is suitable for the on-field experiments and testing of water samples. HMIs (antigen) and thiol-based SAM (antibody) interaction results change in surface morphology and topography. In this study, the authors have used different characterization techniques to check the selectivity of the proposed method. This change in the morphology and topography of thin-film sensor checked with Fourier-transform infrared spectroscopy, surface-enhanced Raman scattering spectroscopy, atomic force microscopy and scanning electron microscopy with energy dispersive x-ray analysis used for high-resolution images.,This thin-film based platform is straightforward to use and suitable for real-time detection of HMIs at the picomolar range. This thin-film based sensor platform capable of achieving a lower limit of detection (LOD) 27.42 ng/mL (136.56 pM) using SAM of Homocysteine-Pyridinedicarboxylic acid to detect Hg2+ ions.,A thin-film based technology is perfect for real-time testing and removal of HMIs, but the LOD is higher as compared to microcantilever-based devices.,The excessive use and commercialization of nanoparticle (NPs) are quickly expanding their toxic impact on health and the environment. The proposed method used the combination of thin-film and NPs, to overcome the limitation of NPs-based technique and have picomolar (136.56 pM) range of HMIs detection. The proposed thin-film-based sensor shows excellent repeatability and the method is highly reliable for toxic Hg2+ ions detection. The main advantage of the proposed thin-film sensor is its ability to selectively remove the Hg2+ ions from water samples just like a filter and a sensor for detection at picomolar range makes this method best among the other current-state of the art techniques.

中文翻译：

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用于选择性检测皮摩尔范围内汞 (Hg2+) 离子的薄膜传感器

本文的目的是提出一种新的基于薄膜的传感器，用于灵敏和选择性地检测水中的汞 (Hg2+) 离子。薄膜平台易于使用且可快速检测皮摩尔范围内的重金属离子 (HMI)。硫醇的离子选择性自组装单层 (SAM) 用于检测 Au/Ti 顶面上方的 HMI。基于薄膜的平台适用于现场实验和水样测试。HMI（抗原）和基于硫醇的 SAM（抗体）相互作用导致表面形态和形貌发生变化。在这项研究中，作者使用了不同的表征技术来检查所提出方法的选择性。用傅里叶变换红外光谱检查薄膜传感器的形态和形貌的这种变化，表面增强拉曼散射光谱、原子力显微镜和扫描电子显微镜以及用于高分辨率图像的能量色散 X 射线分析。这种基于薄膜的平台使用简单，适用于实时检测 HMI皮摩尔范围。这种基于薄膜的传感器平台能够实现检测下限 (LOD) 27.42 ng/mL (136.56 pM)，使用同型半胱氨酸-吡啶二羧酸的 SAM 检测 Hg2+ 离子。 HMI 的时间测试和去除，但与基于微悬臂梁的设备相比，LOD 更高。纳米颗粒 (NP) 的过度使用和商业化正在迅速扩大其对健康和环境的毒性影响。所提出的方法使用薄膜和纳米颗粒的组合，克服基于 NPs 技术的局限性，并具有皮摩尔 (136.56 pM) 范围的 HMI 检测。所提出的基于薄膜的传感器显示出出色的重复性，并且该方法对于有毒 Hg2+ 离子检测具有高度可靠性。所提出的薄膜传感器的主要优点是它能够像过滤器一样选择性地从水样中去除 Hg2+ 离子，而在皮摩尔范围内进行检测的传感器使该方法成为其他当​​前最先进技术中的最佳选择。