Tampons recovered from a cohort of 737 healthy women (median age, 32 years) were analyzed for the presence of Staphylococcus aureus. A total of 198 tampons (27%) were colonized by S. aureus, 28 (4%) by a strain producing toxic shock syndrome toxin 1 (TSST-1). S. aureus was detected more frequently in tampons that did not require an applicator for their insertion (74/233 [32%] versus 90/381 [24%]; odds ratio [OR] = 1.51 [95% confidence interval, 1.04 to 2.17]) and in women who used an intrauterine device for contraception (53/155 [34%] versus 145/572 [27%]; OR = 1.53 [95% confidence interval, 1.05 to 2.24]). The S. aureus strains isolated from tampons belonged to 22 different clonal complexes (CCs). The most prevalent CC was CC398 agr1 (n = 57 [27%]), a clone that does not produce superantigenic toxins, followed by CC30 agr3 (n = 27, 13%), producing TSST-1 (24/27 [89%]), the principal clone of S. aureus involved in menstrual toxic shock syndrome (MTSS).

中文翻译：

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健康女性中金黄色葡萄球菌对阴道棉塞的定植。

分析了从一组737名健康女性（中位年龄为32岁）中恢复的卫生棉条中是否存在金黄色葡萄球菌。金黄色葡萄球菌定殖了总共198个棉塞（27％），产生毒性休克综合症毒素1（TSST-1）的菌株定殖了28个棉塞（4％）。在不需要涂药器的卫生棉条中检出金黄色葡萄球菌的频率更高（74/233 [32％]对90/381 [24％]；优势比[OR] = 1.51 [95％置信区间，1.04至[2.17]和使用宫内节育器避孕的女性（53/155 [34％]对145/572 [27％]； OR = 1.53 [95％置信区间，1.05至2.24]）。的金黄色葡萄球菌从棉塞分离的菌株属于22个不同的克隆物（CC）上。最流行的抄送是CC398agr 1（n = 57 [27％]），不产生超抗原毒素的克隆，然后是CC30 agr 3（n = 27，13 ％），产生TSST-1（24/27 [89％]），金黄色葡萄球菌的主要克隆，涉及月经中毒性休克综合征（MTSS）。