Abstract Over the past few years, there has been an increase in the production of biopolymers, including poly(3-hydroxybutyrate) P(3HB). However, finding compatible solvents for these new materials can be a challenging task. The infinite dilution activity coefficient (IDAC) is a thermodynamic property that indicates the level of interactions between two substances and can be determined from experiments of inverse gas chromatography (IGC). In this work, IGC was used to determine IDAC of 12 solvents in P(3HB). The substances studied were 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), 1,2-dichloroethane, 2,2,2-trifluoroethanol, 2-butanone, 2-heptanone, benzene, chloroform, cyclohexane, dimethyl carbonate, ethyl acetate, isooctane and toluene. HFIP was found to be the most compatible solvent with P(3HB) with IDAC values smaller than 1. Isooctane presented the highest IDAC value, in agreement with the well known incompatibility between hydrocarbons and P(3HB). In addition, P(3HB) crystallinity was determined through IGC technique, enabling the calculation of the IDAC of amorphous phase only, where vapor-liquid equilibrium can be assumed. The degree of crystallinity obtained with HFIP analysis in P(3HB) was 68%, a value close to that previously reported in the literature.

中文翻译：

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反气相色谱法测定聚-3-羟基丁酸酯中溶剂的无限稀释活度系数

摘要 在过去的几年中，生物聚合物的产量有所增加，包括聚（3-羟基丁酸）P(3HB)。然而，为这些新材料寻找兼容的溶剂可能是一项具有挑战性的任务。无限稀释活度系数 (IDAC) 是一种热力学性质，表示两种物质之间的相互作用水平，可以通过逆气相色谱 (IGC) 实验确定。在这项工作中，IGC 用于测定 P(3HB) 中 12 种溶剂的 IDAC。研究的物质是 1,1,1,3,3,3-六氟-2-丙醇 (HFIP)、1,2-二氯乙烷、2,2,2-三氟乙醇、2-丁酮、2-庚酮、苯、氯仿、环己烷、碳酸二甲酯、乙酸乙酯、异辛烷和甲苯。发现 HFIP 是与 IDAC 值小于 1 的 P(3HB) 最相容的溶剂。异辛烷呈现最高的 IDAC 值，这与众所周知的碳氢化合物和 P(3HB) 之间的不相容性一致。此外，P(3HB) 结晶度是通过 IGC 技术确定的，因此可以仅计算非晶相的 IDAC，其中可以假设气液平衡。在 P(3HB) 中用 HFIP 分析获得的结晶度为 68%，该值接近于先前在文献中报道的值。