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Deviant cortical sulcation related to schizophrenia and cognitive deficits in the second trimester
Translational Neuroscience ( IF 1.8 ) Pub Date : 2020-07-15 , DOI: 10.1515/tnsci-2020-0111
Michael Lloyd MacKinley 1, 2 , Priyadharshini Sabesan 3, 4 , Lena Palaniyappan 1, 3, 4
Affiliation  

Aberrant cortical development, inferred from cortical folding, is linked to the risk of schizophrenia. Cortical folds develop in a time-locked fashion during fetal growth. We leveraged this temporal specificity of sulcation to investigate the timing of the prenatal insult linked to schizophrenia and the cognitive impairment seen in this illness.

中文翻译:

与精神分裂症和孕中期认知缺陷相关的异常皮层沟

从皮质折叠推断出的异常皮质发育与精神分裂症的风险有关。皮质褶皱在胎儿生长过程中以时间锁定的方式发育。我们利用这种时间特殊性来研究与精神分裂症相关的产前损伤的时间以及在这种疾病中观察到的认知障碍。
更新日期:2020-07-17
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