Primitive reflexes may reoccur in various neurodegenerative diseases. However, little is known about their structural and functional correlates in the human brain. Notably, the neural mechanisms underlying a positive palmomental reflex (PMR) are poorly understood. As recent studies link Alzheimer's disease (AD)‐related primitive reflexes to a dysfunction of the corticostriatal motor circuit (CMC), we conducted the present study to investigate functional and structural correlates of a positive PMR. We hypothesized an involvement of frontostriatal structures and an impairment of the CMC.

中文翻译：

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掌膜反射阳性的阿尔茨海默氏病的前额窦异常连接。

原始反射可能会在各种神经退行性疾病中再次发生。但是，关于它们在人脑中的结构和功能相关性知之甚少。值得注意的是，对正手掌反射（PMR）的神经机制了解甚少。由于最近的研究将阿尔茨海默氏病（AD）相关的原始反射与皮层运动功能障碍（CMC）相关联，我们进行了本研究以研究阳性PMR的功能和结构相关性。我们假设涉及额骨结构和CMC的损害。