Herein, we present a facile strategy for dopamine (DA) sensing by a water-stable MOF of {[Tb(Cmdcp)(H₂O)₃]₂(NO₃)₂·5H₂O}_n (1, H₃CmdcpBr = N-carboxymethyl-(3,5-dicarboxyl)pyridinium bromide). Without any post-modification, MOF 1 functions as an effective fluorescent sensor for the label-free detection of DA with the detection limit of 0.41 μM (S/N = 3). Under the optimum condition of 80 °C, pH 9 for 80 min in Tris-HCl with natural ambient oxygen, DA polymerizes to give polydopamine (pDA), which adheres to the surface of MOF 1 and quenched its green luminescence thoroughly. The sensing process is visible to naked eyes under 365 nm UV light irradiation due to the partial overlap of its excitation spectrum with the absorption spectrum of pDA. The sensing process is not interfered by coexisting of bio-related organic substances, such as glucose (Glu), 5-hydroxytryptamine (5-HT), homocysteine (Hcy), ascorbic acid (AA), uric acid (UA), cysteine (Cys), glutathione (GSH), as well as the presence of metal ions, including Zn²⁺, Ca²⁺, Mg²⁺, Ni²⁺ and Co²⁺. The sensing process is also adaptable in biological fluids of serum and urine with satisfactory recoveries ranging from 96.14% to 104.32%.

在这里，我们提出了{{Tb（Cmdcp）（H ₂ O）₃ ] ₂（NO ₃）₂ ·5H ₂ O} _n（1，H ₃ CmdcpBr ＝  N-羧甲基-（3，5-二羧基）溴化吡啶鎓）。没有任何后修饰，MOF 1用作DA的具有0.41的检测极限的无标记检测一个有效的荧光传感器 μ M（S / N = 3）。在具有天然环境氧气的Tris-HCl中，在80°C，pH 9的最佳条件下80分钟，DA聚合生成聚多巴胺（pDA），该聚多巴胺（pDA）附着在MOF表面1并彻底淬灭其绿色发光。由于其激发光谱与pDA的吸收光谱部分重叠，因此在365 nm紫外线照射下肉眼可以看到传感过程。葡萄糖（Glu），5-羟基色胺（5-HT），高半胱氨酸（Hcy），抗坏血酸（AA），尿酸（UA），半胱氨酸（ Cys），谷胱甘肽（GSH）以及金属离子（包括Zn 2 ⁺，Ca 2 ⁺，Mg 2 ⁺，Ni ²⁺和Co ^{2+）的存在}。传感过程也适用于血清和尿液的生物体液，回收率从96.14％到104.32％不等。