INTRODUCTION In the current study, we sought to compare baseline demographic, clinical, and operative characteristics, as well as baseline and follow-up patient reported outcomes (PROs) of patients with any depressive and/or anxiety disorder undergoing surgery for low-grade spondylolisthesis using a national spine registry. PATIENTS AND METHODS The Quality Outcomes Database (QOD) was queried for patients undergoing surgery for Meyerding grade 1 lumbar spondylolisthesis undergoing 1-2 level decompression or 1 level fusion at 12 sites with the highest number of patients enrolled in QOD with 2-year follow-up data. RESULTS Of the 608 patients identified, 25.6 % (n = 156) had any depressive and/or anxiety disorder. Patients with a depressive/anxiety disorder were less likely to be discharged home (p < 0.001). At 3=months, patients with a depressive/anxiety disorder had higher back pain (p < 0.001), lower quality of life (p < 0.001) and higher disability (p = 0.013); at 2 year patients with depression and/or anxiety had lower quality of life compared to those without (p < 0.001). On multivariable regression, depression was associated with significantly lower odds of achieving 20 % or less ODI (OR 0.44, 95 % CI 0.21-0.94,p = 0.03). Presence of an anxiety disorder was not associated with decreased odds of achieving that milestone at 3 months. The presence of depressive-disorder, anxiety-disorder or both did not have an impact on ODI at 2 years. Finally, patient satisfaction at 2-years did not differ between the two groups (79.8 % vs 82.7 %,p = 0.503). CONCLUSION We found that presence of a depressive-disorder may impact short-term outcomes among patients undergoing surgery for low grade spondylolisthesis but longer term outcomes are not affected by either a depressive or anxiety disorder.

中文翻译：

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患有抑郁症和/或焦虑症的患者可以在 1 级脊椎滑脱手术后获得最佳长期结果：来自质量结果数据库 (QOD) 的分析

引言 在目前的研究中，我们试图比较基线人口统计学、临床和手术特征，以及患有任何抑郁症和/或焦虑症的患者接受低度滑脱手术的基线和随访患者报告的结果 (PRO)使用国家脊柱登记处。患者和方法 在质量结果数据库 (QOD) 中查询了接受 Meyerding 1 级腰椎滑脱手术的患者，该患者在 12 个部位接受 1-2 节段减压或 1 节段融合术，其中 QOD 入组的患者数量最多，随访 2 年。上数据。结果 在确定的 608 名患者中，25.6 % (n = 156) 患有任何抑郁症和/或焦虑症。患有抑郁症/焦虑症的患者出院回家的可能性较小（p < 0.001）。在 3 = 个月时，患有抑郁症/焦虑症的患者背痛程度更高（p < 0.001），生活质量更低（p < 0.001）和残疾程度更高（p = 0.013）；在 2 年时，患有抑郁症和/或焦虑症的患者的生活质量低于没有抑郁症和/或焦虑症的患者（p < 0.001）。在多变量回归中，抑郁症与达到 20% 或更少 ODI 的几率显着降低相关（OR 0.44，95% CI 0.21-0.94，p = 0.03）。焦虑症的存在与 3 个月时达到该里程碑的几率降低无关。2 年时抑郁症、焦虑症或两者的存在对 ODI 没有影响。最后，两组患者在 2 年时的满意度没有差异（79.8 % 对 82.7 %，p = 0.503）。