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(E)-N-(pyren-1-ylmethylene)benzenamine: efficient promoter for additive-free palladium catalyzed aerobic oxidative coupling of arylboronic acids and terminal alkynes
Chemical Papers ( IF 2.1 ) Pub Date : 2020-04-13 , DOI: 10.1007/s11696-020-01156-8 Jagadeesan Lakshmipraba , Rupesh Narayana Prabhu , Victor Violet Dhayabaran
中文翻译:
(E)-N-(吡喃-1-基亚甲基)苯甲胺:芳基硼酸和末端炔烃的无添加剂钯催化的需氧氧化偶联的有效促进剂
更新日期:2020-04-13
Chemical Papers ( IF 2.1 ) Pub Date : 2020-04-13 , DOI: 10.1007/s11696-020-01156-8 Jagadeesan Lakshmipraba , Rupesh Narayana Prabhu , Victor Violet Dhayabaran
Abstract
A highly productive protocol for the synthesis of internal alkynes by the carbon–carbon cross-coupling reactions of electronically different arylboronic acids with substituted phenylacetylenes was described by employing (E)-N-(pyren-1-ylmethylene)benzenamine with Pd(OAc)2. The influence of reaction parameters such as solvent, base and reaction temperature in this carbon–carbon cross-coupling reaction was also investigated. The substrate scope could be expanded to electron-poor alkynes, for which the conventional Sonogashira reaction gives poor yields. Moderate to excellent yield was obtained in the oxidative Sonogashira-type coupling reaction.Graphic abstract
中文翻译:
(E)-N-(吡喃-1-基亚甲基)苯甲胺:芳基硼酸和末端炔烃的无添加剂钯催化的需氧氧化偶联的有效促进剂