Background Migraine, tension type headache (TTH), and hypothyroidism are clinical problems that affect patient daily activities and quality of life. Objectives The purpose of this study was to investigate the potential association between hypothyroidism in patients with migraine and TTH. Patients and methods Two hundred and twelve patients with migraine and TTH and one hundred control subjects underwent clinical evaluation, assessment of thyroid hormones, and thyroid ultrasound. Results Subclinical and overt hypothyroidism were significantly higher in patients with migraine and TTH ( P = 0.001) than control subjects . Patients with migraine and TTH showed significantly more abnormal thyroid gland morphology than healthy control ( P = 0.027) . Hypothyroidism is significantly expressed in chronic TTH more than TTH with infrequent or frequent TTH ( P = 0.009). Conclusions Patients having migraine and TTH more prone to develop hypothyroidism when compared with control group. Also patients with chronic TTH are susceptible to develop hypothyroidism (either subclinical or overt) when compared with patients having frequent or infrequent TTH.

中文翻译：

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埃及偏头痛和紧张性头痛合并甲状腺功能减退症

背景 偏头痛、紧张型头痛 (TTH) 和甲状腺功能减退症是影响患者日常活动和生活质量的临床问题。目的 本研究的目的是调查偏头痛患者甲状腺功能减退症与 TTH 之间的潜在关联。患者和方法 212 名偏头痛和 TTH 患者和 100 名对照受试者接受了临床评估、甲状腺激素评估和甲状腺超声检查。结果偏头痛和TTH患者的亚临床和明显甲状腺功能减退症显着高于对照组（P=0.001）。偏头痛和 TTH 患者的甲状腺形态异常明显多于健康对照组（ P = 0.027）。甲状腺功能减退症在慢性 TTH 中的表达明显多于 TTH 少见或频繁的 TTH（ P = 0.009）。结论与对照组相比，偏头痛和TTH患者更易发生甲状腺功能减退症。与频繁或不频繁 TTH 的患者相比，慢性 TTH 患者更容易发生甲状腺功能减退症（亚临床或显性）。