Introduction: Although preventive health and therapeutics have benefited from advances in drug development and device innovation, translating these evidence-based treatments into real-world practice remains challenging. Aim: The current integrative review aims to identify facilitators and barriers and perceptions in delivering and managing injectable therapies from patient perspectives. Methods: An integrative review was conducted in the databases of PubMed, CINAHL, PsycINFO and Cochrane. Keywords were used “Injectable therapy”, “IV therapy”, “SC therapy”, “long term injectable therapies”, “self-administered injectable therapy”, “patients”, “caregivers”, “family”, “carers”, “facilitators”, “barriers”, “perspectives”, “needs”, “expectations”, “chronic disease”, “cardiovascular disease” linked with the words “OR” and “AND”. The search was limited from January 2000 to July 2019. Inclusion and exclusion criteria were used. Results: Twenty studies were identified from the literature search. Studies followed qualitative, quantitative methodology and mixed methods. Facilitators included: health improvement, prevention of disease complications, taking control of their disease, effectiveness of the medication and convenience in management. Barriers included: fear of needles, insulin will cause harm, poor perception of the benefits of injectable therapies on their quality of life, inconvenience in self-management, social stigma, impact on daily living, financial barriers, lack of education. Perceptions included: ‘treatment of last resort’, ‘life becomes less flexible’, ‘injectables were punishment/restriction’, ‘personal failure of self-management’. Conclusion: Evidence shows how to create effective communication and shared decision-making relationships to provide best possible care to patients who need injectable therapy and support for self-management. Future research might help guide response to the fears and barriers of the patients using patients’ perspectives.

中文翻译：

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对慢性病中提供和管理注射疗法的促进因素和障碍的综合审查：ACNAP 项目“心血管疾病患者的注射药物”的一部分

简介：虽然预防性健康和治疗已经受益于药物开发和设备创新的进步，但将这些基于证据的治疗转化为现实世界的实践仍然具有挑战性。目的：目前的综合审查旨在从患者的角度确定提供和管理注射疗法的促进因素、障碍和看法。方法：在 PubMed、CINAHL、PsycINFO 和 Cochrane 的数据库中进行综合评价。关键词被使用“注射疗法”、“IV疗法”、“SC疗法”、“长期注射疗法”、“自我注射疗法”、“患者”、“照顾者”、“家庭”、“照顾者”、“ “促进者”、“障碍”、“观点”、“需要”、“期望”、“慢性病”、“心血管疾病”，这些词与“或”和“与”相关联。搜索范围从 2000 年 1 月到 2019 年 7 月。使用了纳入和排除标准。结果：从文献检索中确定了 20 项研究。研究遵循定性、定量方法和混合方法。促进因素包括：健康改善、疾病并发症的预防、疾病的控制、药物的有效性和管理的便利性。障碍包括：害怕针头、胰岛素会造成伤害、对注射疗法对其生活质量的益处认识不足、自我管理不便、社会污名、对日常生活的影响、经济障碍、缺乏教育。看法包括：“最后手段的治疗”、“生活变得不那么灵活”、“注射剂是惩罚/限制”、“自我管理的个人失败”。结论：证据表明如何建立有效的沟通和共享决策关系，为需要注射治疗和自我管理支持的患者提供最佳护理。未来的研究可能有助于利用患者的观点来指导对患者的恐惧和障碍的反应。