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Physiological wound assessment from coregistered and segmented tissue hemoglobin maps.
Journal of the Optical Society of America A ( IF 1.4 ) Pub Date : 2020-07-20 , DOI: 10.1364/josaa.394985
E A Robledo , R Schutzman , R Fang , C Fernandez , R Kwasinski , K Leiva , F Perez-Clavijo , A Godavarty

A handheld near-infrared optical scanner (NIROS) was recently developed to map for effective changes in oxy- and deoxyhemoglobin concentration in diabetic foot ulcers (DFUs) across weeks of treatment. Herein, a coregistration and image segmentation approach was implemented to overlay hemoglobin maps onto the white light images of ulcers. Validation studies demonstrated over 97% accuracy in coregistration. Coregistration was further applied to a healing DFU across weeks of healing. The potential to predict changes in wound healing was observed when comparing the coregistered and segmented hemoglobin concentration area maps to the visual area of the wound.

中文翻译:

从共同登记和分割的组织血红蛋白图进行生理伤口评估。

最近开发了一种手持式近红外光学扫描仪(NIROS),以绘制治疗几周后糖尿病足溃疡(DFU)中氧和脱氧血红蛋白浓度的有效变化图。在本文中,实施了配色和图像分割方法以将血红蛋白图谱叠加在溃疡的白光图像上。验证研究表明,整合的准确性超过97%。在康复的数周内,Coregistration进一步应用于康复的DFU。当将共配准和分段的血红蛋白浓度区域图与伤口的可视区域进行比较时,观察到了预测伤口愈合变化的潜力。
更新日期:2020-08-01
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