The catalytic conversion of (ligno)cellulose is currently subject of intense research. Isosorbide is one of the interesting products that can be produced from (ligno)cellulose as it can be used for the synthesis of a wide range of pharmaceuticals, chemicals, and polymers. Isosorbide is obtained after the hydrolysis of cellulose to glucose, followed by the hydrogenation of glucose to sorbitol that is then dehydrated to isosorbide. The one-pot process requires an acid and a hydrogenation catalyst. Several parameters are of importance during the direct conversion of (ligno)cellulose such as the acidity, the crystallinity and the particle size of cellulose as well as the nature of the feedstocks. This review highlights all these parameters and all the strategies employed to produce isosorbide from (ligno)cellulose in a one-pot process.

中文翻译：

---

从纤维素或木质纤维素生物质一锅合成异山梨醇：挑战？


（木质）纤维素的催化转化目前是深入研究的主题。异山梨醇是可由（木质）纤维素生产的有趣产品之一，因为它可用于合成各种药物、化学品和聚合物。纤维素水解为葡萄糖，然后葡萄糖加氢为山梨醇，然后脱水为异山梨醇，得到异山梨醇。一锅法需要酸和加氢催化剂。在（木质）纤维素的直接转化过程中，有几个参数非常重要，例如纤维素的酸度、结晶度和粒度以及原料的性质。本综述重点介绍了所有这些参数以及在一锅法中从（木质）纤维素生产异山梨醇所采用的所有策略。