Identification and structural characterization of lipid A from Escherichia coli, Pseudomonas putida and Pseudomonas taiwanensis by liquid chromatography coupled to high resolution-tandem mass spectrometry.,Rapid Communications in Mass Spectrometry

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Identification and structural characterization of lipid A from Escherichia coli, Pseudomonas putida and Pseudomonas taiwanensis by liquid chromatography coupled to high resolution-tandem mass spectrometry.
Rapid Communications in Mass Spectrometry ( IF 1.8 ) Pub Date : 2020-07-16 , DOI: 10.1002/rcm.8897
Matti Froning ₁ , Patrick O Helmer ₁ , Heiko Hayen ₁

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Lipid A is a part of the lipopolysaccharide layer, which is a main component of the outer membrane from Gram‐negative bacteria. It can be sensed by mammalians to identify the presence of Gram‐negative bacteria in their tissues and plays a key role in the pathogenesis of bacterial infections. Lipid A is also used as an adjuvant in human vaccines, emphasizing the importance of its structural analysis.

更新日期：2020-08-20

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