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Meteoric synthesis of Luminescent Fe2O3 Nanoparticles: A potential Cytotoxic, Antioxidant & Bactericidal agent
International Journal of Applied Ceramic Technology ( IF 1.8 ) Pub Date : 2020-07-16 , DOI: 10.1111/ijac.13591
Gavini Deepthi Reddy 1 , Mohammed Noorjahan 1 , Annapragada Ratnamala 2 , Mohammed Haseena 2 , Hanumanthrayappa Manjunatha 2 , Kadiyala Chandra Babu Naidu 3
Affiliation  

Here we report the meteoric synthesis of luminescent nanomagnetic Fe2O3 (LNM Fe2O3) particles using green sources ie, microwave energy of 800 W and Hibiscus rosasinensis (H rosasinensis) leaf extract with high anti oxidant and anti cancer properties as an active surfactant. The microwave irradiation times for the synthesis of LNM Fe2O3 particles were optimized. Structural morphology, magnetic and optical properties of synthesized LNM Fe2O3 particles was studied using different analytical techniques. The data clearly indicated that H rosasinensis leaf extract‐mediated LNM Fe2O3 particles are spherical in shape with the presence of both α‐Fe2O3 and small amounts of ϒ ‐ Fe2O3 phases which have smaller size and larger surface area with slight agglomeration. Cytotoxic activities were performed on HCT‐116, HeLa and MCF‐7 cancer cell lines using MTT assay, antioxidant ability was determined using DPPH assay and bactericidal activity studies performed on Gram‐negative E coli bacteria and Gram‐positive bacteria Bacillus subtilis for the synthesized LNM Fe2O3 particles which were found to be highly efficient. Biological studies revealed that synthesized luminescent nanomagnetic Fe2O3 particles act as potential cytotoxic, antioxidant and bactericidal agent.

中文翻译:

Fe2O3发光纳米粒子的流星合成:潜在的细胞毒性,抗氧化剂和杀菌剂

在这里,我们报道了使用绿色能源(即800 W的微波能量)和芙蓉玫瑰花(H rosasinensis)叶提取物的流态合成发光纳米磁性Fe 2 O 3(LNM Fe 2 O 3)颗粒的方法,该提取物具有很高的抗氧化剂和抗癌特性活性表面活性剂。优化了合成LNM Fe 2 O 3的微波辐射时间。使用不同的分析技术研究了合成的LNM Fe 2 O 3颗粒的结构形态,磁性和光学性质。数据清楚地表明,玫瑰红叶提取物介导的LNM Fe2个ö 3颗粒是球形与两者的α-Fe存在2 ö 3和少量的Υ -铁2个ö 3相具有更小的尺寸,并用轻微结块较大的表面积。使用MTT测定法对HCT-116,HeLa和MCF-7癌细胞系进行细胞毒活性,使用DPPH测定法测定抗氧化能力,并对革兰氏阴性大肠杆菌枯草芽孢杆菌进行枯草芽孢杆菌杀菌活性研究LNM铁2 O 3被发现是高效的颗粒。生物学研究表明,合成的发光纳米磁性Fe 2 O 3颗粒具有潜在的细胞毒性,抗氧化剂和杀菌作用。
更新日期:2020-07-16
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