Wound dressings are based on the creation of ideal environments for cell mobility, gas exchanges and to promote tissue healing and regeneration, besides controlling bacterial proliferation. Electrospinning is a simple, cheap and common technique used for such purposes and Ecovio®, a polymeric blend based on biocompatible polymers (poly(butylene adipate-co-terephthalate) (PBAT) and poly(lactic acid) (PLA)), is a good example of polymer with unique properties for wound dressing materials development. To ensure antimicrobial properties, Job’s tears (Coix lacrymajobi) extract was incorporated into the material. The obtained fiber mats were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffractometry (DRX), optical microscopy (OM), and microbiological analysis. The interaction among the compounds of the extract and the polymeric matrix was inferred by the increase in the crystallinity degree and thermal stability of the fibers/extract. Also, a decrease in the diameter, roughness, and fiber homogeneity was observed. It happened due to the presence of extract in the fibers. Microbiological analysis (antimicrobial activity against S. aureus) indicated the effectiveness of the fibers/extract in preventing this bacteria growth, demonstrating the potential of this material for wound dressing purposes.

中文翻译：

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Co仁胶乳-乔比提取物的聚合物微纤维的抗菌活性

伤口敷料的基础是创造理想的环境，以控制细胞增殖，促进细胞迁移，气体交换并促进组织愈合和再生。电纺丝是用于此目的的一种简单，廉价且通用的技术，Ecovio®是一种基于生物相容性聚合物（聚（己二酸丁二酯-对苯二甲酸对苯二甲酸酯）（PBAT）和聚乳酸（PLA））的聚合物共混物。具有独特特性的聚合物在伤口处理材料开发方面的良好范例。为了确保抗菌性能，乔布斯的眼泪（Coix lacrymajobi）提取物被合并到材料中。通过傅里叶变换红外光谱（FTIR），扫描电子显微镜（SEM），差示扫描量热法（DSC），热重分析（TGA），X射线衍射（DRX），光学显微镜（OM）和微生物分析。提取物的化合物与聚合物基质之间的相互作用可通过纤维/提取物的结晶度和热稳定性的增加来推断。另外，观察到直径，粗糙度和纤维均匀性的降低。这是由于纤维中存在提取物而发生的。微生物分析（对金黄色葡萄球菌的抗菌活性）表明了纤维/提取物在防止这种细菌生长方面的有效性，证明了这种材料在伤口包扎方面的潜力。