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The prevalence of sleep-disordered breathing in Northwest Russia: The ARKHsleep study.
Chronic Respiratory Disease ( IF 3.5 ) Pub Date : 2020-07-15 , DOI: 10.1177/1479973120928103
Anna Khokhrina 1, 2 , Elena Andreeva 2 , Jean-Marie Degryse 1, 3
Affiliation  

Sleep-disordered breathing (SDB) is a chronic condition characterized by repeated breathing pauses during sleep. The reported prevalence of SDB in the general population has increased over time. Furthermore, in the literature, a distinction is made between SDB, obstructive sleep apnea (OSA), and “OSA syndrome” (OSAS). Patients with SDB are at increased risk of comorbid cardiovascular diseases (CVDs). The aim of the ARKHsleep study was to assess the prevalence of SDB in general and of OSA and OSAS in particular. A total of 1050 participants aged 30–70 years, who were randomly selected from a population register, were evaluated for the probability of SDB using the Epworth Sleepiness Scale score and body mass index. Sleep was recorded for one night via home sleep apnea testing (Somnolter®). Medical conditions were determined from medical records. Additional data included background characteristics, anthropometric variables, blood pressure, and scores from four questionnaires. The survey sample consisted of 41.2% males and had a mean age of 53.1 ± 11.3 years. The prevalence of mild-to-severe, moderate-to-severe, and severe SDB was 48.9% [45.8–51.9], 18.1% [15.9–20.6], and 4.5% [3.2–5.8], respectively. Individuals reporting snoring or breathing pauses had a higher severity of SDB than individuals free of symptoms. The ARKHsleep study revealed a high burden of both SDB and CVD; however, more large-scale cohort studies and intervention studies are needed to better understand whether the early recognition and treatment of mild SDB with or without symptoms will improve cardiovascular prognosis and/or quality of life.



中文翻译:


俄罗斯西北部睡眠呼吸障碍的患病率:ARKHsleep 研究。



睡眠呼吸障碍 (SDB) 是一种慢性疾病,其特征是睡眠期间反复出现呼吸暂停。据报道,一般人群中 SDB 的患病率随着时间的推移而增加。此外,文献中对 SDB、阻塞性睡眠呼吸暂停 (OSA) 和“OSA 综合征”(OSAS) 进行了区分。 SDB 患者合并心血管疾病 (CVD) 的风险增加。 ARKHsleep 研究的目的是评估 SDB 的总体患病率,特别是 OSA 和 OSAS 的患病率。从人口登记册中随机抽取 1050 名 30-70 岁的参与者,使用 Epworth 嗜睡量表评分和体重指数评估 SDB 的概率。通过家庭睡眠呼吸暂停测试 (Somnolter®) 记录一晚的睡眠情况。医疗状况是根据医疗记录确定的。其他数据包括背景特征、人体测量变量、血压和四份问卷的得分。调查样本由 41.2% 男性组成,平均年龄为 53.1 ± 11.3 岁。轻度至重度、中度至重度和重度 SDB 的患病率分别为 48.9% [45.8–51.9]、18.1% [15.9–20.6] 和 4.5% [3.2–5.8]。报告打鼾或呼吸暂停的个体比没有症状的个体具有更高的 SDB 严重程度。 ARKHsleep 研究揭示了 SDB 和 CVD 的高负担;然而,需要更大规模的队列研究和干预研究来更好地了解早期识别和治疗有或没有症状的轻度 SDB 是否会改善心血管预后和/或生活质量。

更新日期:2020-07-15
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