Little is known about how individual behavioral and psychological symptoms of dementia (BPSD) impact the person with dementia. This cross-sectional, retrospective study examined the association between one BPSD, aggressive behavior, and a patient-identified outcome, sadness, among people with moderate and severe dementia (n = 5001) using clinical administrative Resident Assessment Instrument 2.0 data. For people with moderate or severe cognitive impairment, the odds of sadness were significantly higher if verbal aggression was exhibited 4 to 6 (adjusted odds ratio [aOR] = 2.85, P < .001) or 1 to 3 (aOR = 2.28, P < .001) times per week, or daily (aOR = 1.77, P = .003). People with severe cognitive impairment and who displayed physical aggression either daily (OR = 2.16, P = .002) or 1 to 3 times per week (OR = 1.45, P = .023) also had an increased odds of sadness. Aggression may harm the person with dementia’s mental well-being, depending on the level of cognitive impairment, and type and frequency of aggression. Prospective studies can build on these correlational findings.

关于痴呆症的个体行为和心理症状如何影响痴呆症的人知之甚少。这项横断面回顾性研究使用临床行政居民评估仪器2.0数据，检查了中度和重度痴呆患者（n = 5001）中一种BPSD，攻击行为与患者识别的结果，悲伤之间的关联。对于中度或重度认知障碍的人，如果言语攻击表现为4到6（调整后的优势比[aOR] = 2.85，P <.001）或1-3（aOR = 2.28，P <每周或每天（.OR = 1.77，P 0.001次）= .003）。患有严重认知障碍并且每天表现出身体攻击性（OR = 2.16，P = .002）或每周出现1至3次（OR = 1.45，P = .023）的人，悲伤的几率也增加了。侵略可能会损害痴呆症患者的心理健康，这取决于认知障碍的程度，侵略的类型和频率。前瞻性研究可以基于这些相关发现。