Salmonella enterica subsp. diarizonae serotype 61: k: 1,5, (7) (SED) is a microorganism well adapted to sheep; however, it has also been described producing chronic proliferative rhinitis (CPR) in ovine. CPR causes a proliferative inflammation of the ventral nasal turbinates that may totally obstruct the nasal cavity.

The main objective of the present study was to investigate the prevalence of SED in nostrils and stool of sheep without CPR clinical signs in commercial sheep farms of Spain with and without previous clinical cases of CPR.

Five samplings were performed in 10 commercial sheep farms for one year. Samples from nostrils and faeces were taken from four animals without CPR visible clinical signs that belonged to four different age ranges at each farm visit.

The prevalence of positive animals was 45.3 %, and the number of positive samples in nostrils was higher than in faeces (38.5 % vs 22.5 %). Only on one farm was no positive result obtained in the entire study. In almost all positive farms, sheep belonging to the youngest age ranges accounted for more than 50 % of positive isolates. Finally, farms with a previous diagnosis of CPR were 1.784 times more likely to have an animal with positive isolation than farms without a previous diagnosis. This could suggest that the infection pressure in the farm might favour the occurrence of clinical cases of the disease. However, further studies will be necessary to unravel why this saprophytic bacterium is able to cross the epithelial barrier causing severe rhinitis in certain animals.

肠沙门氏菌亚种。Diarizonae血清型61：k：1,5，（7）（SED）是一种非常适合绵羊的微生物；然而，也已经描述了在绵羊中产生慢性增生性鼻炎（CPR）。CPR引起腹鼻甲的增生性炎症，可能会完全阻塞鼻腔。

本研究的主要目的是调查西班牙商业绵羊场中有无CPR临床症状的无CPR临床体征的绵羊鼻孔和粪便中SED的患病率。

在10个商业羊场中进行了5次采样，为期一年。取自四只动物的鼻孔和粪便样本，这些动物没有CPR可见的临床体征，每次农场访问时都属于四个不同的年龄范围。

阳性动物的患病率为45.3％，鼻孔中的阳性样本数量高于粪便（38.5％比22.5％）。在整个研究中，只有一个农场没有获得阳性结果。在几乎所有阳性养殖场中，年龄最小的绵羊占阳性分离株的50％以上。最终，先前诊断为CPR的农场拥有隔离阳性动物的可能性是没有先前诊断的农场的1.784倍。这可能表明农场的感染压力可能会促进该疾病临床病例的发生。但是，有必要进行进一步的研究来阐明为什么这种腐生细菌能够穿过上皮屏障，从而在某些动物中引起严重的鼻炎。