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Light-induced liposomes for cancer therapeutics.
Progress in Lipid Research ( IF 14.0 ) Pub Date : 2020-07-15 , DOI: 10.1016/j.plipres.2020.101052
Wenjie Chen 1 , Ewa M Goldys 2 , Wei Deng 2
Affiliation  

The emerging nanomedicine therapeutics have incorporated photonics technologies to develop precise medical treatment. Among the light regulated approaches, light-induced liposome technology has been explored and developed as a novel tool for spatiotemporal control of cargo release. Compared with the traditional liposome formulation, this triggering feature largely enhanced the therapeutic efficacy and minimized the side effects of the therapeutic substance. In this review paper, we discussed the basics of the light-induced liposomes including the engineering methods and photoresponsiveness mechanisms. We also reviewed current biomedical studies relating to light-induced liposome delivery systems, with an emphasis in the field of cancer therapy.



中文翻译:

光致脂质体用于癌症治疗。

新兴的纳米医学疗法已经结合了光子学技术,以开发精确的医学疗法。在光调节方法中,已经探索和开发了光诱导脂质体技术,作为一种用于时空控制货物释放的新型工具。与传统脂质体制剂相比,该触发特征大大增强了治疗功效,并使治疗物质的副作用最小化。在这篇综述文章中,我们讨论了光诱导脂质体的基础知识,包括工程方法和光响应机制。我们还回顾了与光诱导脂质体递送系统相关的当前生物医学研究,重点是癌症治疗领域。

更新日期:2020-07-15
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